Monthly Archives: September 2014

F1000 Commentary: Treatment of adults with complications from previous hypospadias surgery

Myers JB, McAninch W, Erickson BA, Breyer BN. J Urol. 2012 Aug;188(2):459-63 DOI: 10.1016/j.juro.2012.04.007 Abstract Purpose: Adults with complications from previous hypospadias surgery experience various problems, including urethral stricture, persistent hypospadias and urethrocutaneous fistula. Innate deficiencies of the corpus spongiosum and … Continue reading

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F1000 Commentary: Phenotypical, biological, and molecular heterogeneity of 5alpha-reductase deficiency: an extensive international experience of 55 patients

Maimoun L, Philibert P, Cammas B, Audran F, Servant N, Lubroso S, Paris F, Sultan C. J Clin Endocrinol Metab. 2011 Feb; 96:296-307 DOI: 10.1210/jc.2010-1024 Abstract CONTEXT: In 46,XY disorders of sex development, 5α-reductase deficiency is rare and is not usually … Continue reading

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F1000 Commentary: Disorders of sex development-when and how to tell the patient

Austin J, Tamar-Mattis A, Mazur T, Henwood MJ, Rossi WC. Pediatr Endocrinol Rev. 2011;8:213-7 Abstract   Physicians and other providers are often confronted with difficult decisions in the area of disclosure. This article examines a hypothetical situation relevant to the practice … Continue reading

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F1000 Commentary: Working together in placing the long term interests of the child at the heart of the DSD evaluation.

Magritte E. J Pediatr Urol. 2012 Dec; 8(6):571-5 DOI: 10.1016/j.jpurol.2012.07.011 Abstract    This paper articulates a number of important but often ignored questions that families have during and following the diagnosis of a child with a DSD. Recounting a personal birth experience, … Continue reading

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F1000 Commentary: Shaping parents: impact of contrasting professional counseling on parents’ decision making for children with disorders of sex development

Streuli JC, Vayena E, Cavicchia-Balmer Y, Huber J. J Sex Med. 2013 Aug; 10(8): 1953-60. DOI: 10.3410/f.718052034.793481314 Abstract    INTRODUCTION: The management of disorders or differences of sex development (DSD) remains complex, especially with respect to parents’ decision for or against … Continue reading

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F1000 Commentary: Sexual and functional results after creation of a neovagina in women with Mayer-Rokitansky-Kuster-Hauser syndrome: a comparison of nonsurgical and surgical procedures

Morcel k, Lavoue V, Jaffre F, Paniel BJ, Rouzier R. Eur J Obstet Gynecol Reprod Biol. 2013 Jul. DOI: 10.1016/j.ejogrb.2013.03.005    Abstract     Objective: To compare nonsurgical and surgical procedures for creation of a neovagina in women with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome in … Continue reading

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F1000 Commentary: Sexual function and surgical outcome in women with congential adrenal hyperplasia due to CYP21A2 deficiency: clinical perspective and the patient’s perception.

Nordenstrom A, Frisen L, Falhammar H, Filipsson H, Janson PO, Thoren M, Hagenfeldt K, Nordskjold A. J Clin Endocrinol Metab. 2010 Aug; 95(8):3633-40 Abstract Context: Females with congenital adrenal hyperplasia (CAH) due to a CYP21A2 deficiency are exposed to androgens … Continue reading

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F1000 Commentary: Ethical principles and recommendations for the medical management of differences of sex development (DSD)/intersex in children and adolescents

Wiesemann C, Ude-koeller S, Sinnecker GH, Thyen U. Eur J Pediatr. 2010 Jun; 169(6):671-9 DOI: 10.1007/s00431-009-1086-x Abstract  The medical management of differences of sex development (DSD)/intersex in early childhood has been criticized by patients’ advocates as well as bioethicists from an … Continue reading

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F1000 Commentary: Decisional regret after distal hypospadias repair: single institution prospective analysis of factors associated with subsequent parental remorse of distress

Lorenzo AJ, Pippi Salle JL, Zlateska B, Koyle MA, Bagli DJ, Braga LH, J Urol. 2014 May DOI: 10.1016/j.juro.2013.10.036 Abstract    Purpose: Hypospadias repair is a commonly performed procedure. Little is known about decisional regret in parents who agree to proceed … Continue reading

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F1000 Commentary: Long term psychological and sexual outcomes of severe penile hypospadias repair

Kiss A, Sulya B, Szász AM, Romics I, Kelemen Z, Tóth J, Merksz M, Kemény S, Nyírády P. J Sex Med. 2011 May; 8(5):1529-39 DOI: 10.1111/j.1743-6109.2010.02120.x Abstract   INTRODUCTION: Hypospadias is the most common penis malformation, and there exist a variety of surgical approaches used to correct the abnormal position of the meatus. … Continue reading

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