Category Archives: F1000 Archives

F1000 Commentary: Attitudes towards “disorders of sex development” nomenclature among affected individuals.

Johnson EK, Rosoklija I, Finlayson C, Chen D, Yerkes EB, Madonna MB, Holl JL,Baratz AB, Davis G, Cheng EY. J Pediatr Urol 2017 May 08 DOI: 10.1016/j.jpurol.2017.03.035 Abstract Introduction Although now commonly used in medicine, the updated “disorders of sex development” (DSD) nomenclature formally introduced in 2006 has never been … Continue reading

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F1000 Commentary: Changes over time in sex assignment for disorders of sex development.

Kolesinska Z, Ahmed SF, Niedziela M, Bryce J, Molinska-Glura M, Rodie M, Jiang J, Sinnott RO, Hughes IA, Darendelier F, Hiort O, van der Zwan Y, Cools M, Guran T, Holterhus PM, Bertelloni S, Lisa L, Arlt W, Krone N, … Continue reading

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F1000 Commentary: Brain responses to sexual images in 46, XY women with complete androgen insensitivity syndrome are female typical.

Hamann S, Stevens J, Vick JH, Bryk K, Quigley CA, Berenbaum SA, Wallen K. Horm. Behav. 2014 Oct 2 DOI:10.1016/j.yhbeh.2014.09.013 Abstract   Androgens, estrogens, and sex chromosomes are the major influences guiding sex differences in brain development, yet their relative … Continue reading

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F1000 Commentary: Treatment of adults with complications from previous hypospadias surgery

Myers JB, McAninch W, Erickson BA, Breyer BN. J Urol. 2012 Aug;188(2):459-63 DOI: 10.1016/j.juro.2012.04.007 Abstract Purpose: Adults with complications from previous hypospadias surgery experience various problems, including urethral stricture, persistent hypospadias and urethrocutaneous fistula. Innate deficiencies of the corpus spongiosum and … Continue reading

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F1000 Commentary: Phenotypical, biological, and molecular heterogeneity of 5alpha-reductase deficiency: an extensive international experience of 55 patients

Maimoun L, Philibert P, Cammas B, Audran F, Servant N, Lubroso S, Paris F, Sultan C. J Clin Endocrinol Metab. 2011 Feb; 96:296-307 DOI: 10.1210/jc.2010-1024 Abstract CONTEXT: In 46,XY disorders of sex development, 5α-reductase deficiency is rare and is not usually … Continue reading

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F1000 Commentary: Disorders of sex development-when and how to tell the patient

Austin J, Tamar-Mattis A, Mazur T, Henwood MJ, Rossi WC. Pediatr Endocrinol Rev. 2011;8:213-7 Abstract   Physicians and other providers are often confronted with difficult decisions in the area of disclosure. This article examines a hypothetical situation relevant to the practice … Continue reading

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F1000 Commentary: Working together in placing the long term interests of the child at the heart of the DSD evaluation.

Magritte E. J Pediatr Urol. 2012 Dec; 8(6):571-5 DOI: 10.1016/j.jpurol.2012.07.011 Abstract    This paper articulates a number of important but often ignored questions that families have during and following the diagnosis of a child with a DSD. Recounting a personal birth experience, … Continue reading

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F1000 Commentary: Shaping parents: impact of contrasting professional counseling on parents’ decision making for children with disorders of sex development

Streuli JC, Vayena E, Cavicchia-Balmer Y, Huber J. J Sex Med. 2013 Aug; 10(8): 1953-60. DOI: 10.3410/f.718052034.793481314 Abstract    INTRODUCTION: The management of disorders or differences of sex development (DSD) remains complex, especially with respect to parents’ decision for or against … Continue reading

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F1000 Commentary: Sexual and functional results after creation of a neovagina in women with Mayer-Rokitansky-Kuster-Hauser syndrome: a comparison of nonsurgical and surgical procedures

Morcel k, Lavoue V, Jaffre F, Paniel BJ, Rouzier R. Eur J Obstet Gynecol Reprod Biol. 2013 Jul. DOI: 10.1016/j.ejogrb.2013.03.005    Abstract     Objective: To compare nonsurgical and surgical procedures for creation of a neovagina in women with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome in … Continue reading

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F1000 Commentary: Sexual function and surgical outcome in women with congential adrenal hyperplasia due to CYP21A2 deficiency: clinical perspective and the patient’s perception.

Nordenstrom A, Frisen L, Falhammar H, Filipsson H, Janson PO, Thoren M, Hagenfeldt K, Nordskjold A. J Clin Endocrinol Metab. 2010 Aug; 95(8):3633-40 Abstract Context: Females with congenital adrenal hyperplasia (CAH) due to a CYP21A2 deficiency are exposed to androgens … Continue reading

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