Category Archives: F1000 Archives

F1000 Commentary: Ethical principles and recommendations for the medical management of differences of sex development (DSD)/intersex in children and adolescents

Wiesemann C, Ude-koeller S, Sinnecker GH, Thyen U. Eur J Pediatr. 2010 Jun; 169(6):671-9 DOI: 10.1007/s00431-009-1086-x Abstract  The medical management of differences of sex development (DSD)/intersex in early childhood has been criticized by patients’ advocates as well as bioethicists from an … Continue reading

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F1000 Commentary: Decisional regret after distal hypospadias repair: single institution prospective analysis of factors associated with subsequent parental remorse of distress

Lorenzo AJ, Pippi Salle JL, Zlateska B, Koyle MA, Bagli DJ, Braga LH, J Urol. 2014 May DOI: 10.1016/j.juro.2013.10.036 Abstract    Purpose: Hypospadias repair is a commonly performed procedure. Little is known about decisional regret in parents who agree to proceed … Continue reading

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F1000 Commentary: Long term psychological and sexual outcomes of severe penile hypospadias repair

Kiss A, Sulya B, Szász AM, Romics I, Kelemen Z, Tóth J, Merksz M, Kemény S, Nyírády P. J Sex Med. 2011 May; 8(5):1529-39 DOI: 10.1111/j.1743-6109.2010.02120.x Abstract   INTRODUCTION: Hypospadias is the most common penis malformation, and there exist a variety of surgical approaches used to correct the abnormal position of the meatus. … Continue reading

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F1000 Commentary: Evaluation of terminology used to describe disorders of sex development

Davies JH, Knight EJ, Savage A, Brown J, Malone PS. J Pediatr Urol. 2011 Aug; 7(4):412-5 DOI:10.1016/j.jpurol.2010.07.004 Abstract   OBJECTIVE: The terminology used to describe abnormalities of sex determination and sex differentiation was revised in 2006. It was anticipated that new terms, such as ‘disorders of sex development’ … Continue reading

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F1000 Commentary: Prenatal Dexamethasone Treatment of Children at Risk for Congenital Adrenal Hyperplasia: The Swedish Experience and Standpoint

Hirvikoski T, Nordenstrom A, Wedell A, Ritzen M, Lajic S. J Clin Endocrinol Metab. 2012 Mar 30 DOI: 10.3410/f.717747955.793302809 _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ … Continue reading

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F1000 Commentary: High prevalence of micropenis in 2710 male newborns from an intensive-use pesticide area of Northeastern Brazil

Gaspari L, Sampaio DR, Paris F, Audran F, Orsini M, Neto JB, Sultan C. DOI:10.3410/f.717973543.793470158 Abstract  Exposure to endocrine-disrupting chemicals (EDCs) has been suggested to contribute to the increasing trends of external genital malformation in male newborns. In Northeastern Brazil, … Continue reading

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F1000 Commentary: Satisfaction with genital surgery and sexual life of adults with XY disorders of sex development: results from the German clinical evaluation study.

Hirvikoski T, Nordenström A, Wedell A, Ritzén M, Lajic S. J Clin Endocrinol Metab. 2012 Mar 30 DOI: 10.1210/jc.2012-1222 Abstract  Background:Prenatal deficit of androgens or androgen action results in atypical genitalia in individuals with XY disorders of sex development (XY,DSD). XY,DSD include mainly disorders of gonadal development … Continue reading

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F1000 Commentary: Gender Identity and Coping in Female 46, XY Adults with Androgen Biosynthesis Deficiency (Intersexuality/DSD)

Schweizer K, Brunner F, Schonbucher V, Richter-Appelt H. J Couns Psychol. 2009; 56:189-201 DOI: 10.1037/a0013575 Abstract Individuals living with an intersex condition have not received much attention in counseling psychology, although a high need for psychosocial care is obvious. Using a … Continue reading

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F1000 Commentary: Genital surgery for disorders of sex development: implementing a shared decision-making approach

Karkazis K, Tamar-Mattis A, Kon AA.. J Pediatr Endorinol Metab. 2010;23:789-806 DOI: 10.1515/jpem.2010.129 Abstract   Ongoing controversy surrounds early genital surgery for children with disorders of sex development, making decisions about these procedures extraordinarily complex. Professional organizations have encouraged healthcare providers to … Continue reading

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F1000 Commentary: Disorders of Sex Development-When and How to Tell the Patient

Austin J, Tamar-Mattis A, Mazur T, Henwood MJ, Rossi WC: Pediatr Endocrinol Rev. 2011; 8:213-7 DOI: 10.3410/f.13398997.14768117 Abstract Physicians and other providers are often confronted with difficult decisions in the area of disclosure. This article examines a hypothetical situation relevant to … Continue reading

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